Accession ID: MIRT003369 [miRNA, hsa-miR-20a-5p :: PTEN, target gene]
pre-miRNA Information
pre-miRNA ID hsa-mir-20aLinkOut: [miRBase ]
Synonyms MIR20, MIRN20, MIRN20A, hsa-mir-20, hsa-mir-20a, miR-20, miRNA20A, MIR20A
Description Homo sapiens miR-20a stem-loop
2nd Structure of pre-miRNA
Disease
Mature miRNA Information
Mature miRNA hsa-miR-20a-5p
Mature Sequence 8| UAAAGUGCUUAUAGUGCAGGUAG |30
Evidence Experimental
Experiments Cloned
Putative hsa-miR-20a-5p Targets LinkOut: [ TargetScanS 5.1 | MicroCosm | microRNA.org | miRecords | miRDB | miRo | miRNAMap 2.0 ]
Gene Information
Gene Symbol PTEN LinkOut: [ Entrez Gene | BioGPS | Wikipedia | iHop ]
Synonyms 10q23del, BZS, DEC, MGC11227, MHAM, MMAC1, PTEN1, TEP1
Description phosphatase and tensin homolog
Transcript NM_0003    LinkOut: [ RefSeq ]
Expression LinkOut: [ BioGPS ]
Putative miRNA Targets on PTEN LinkOut: [ TargetScan 5.1 | MicroCosm | miRNAMap 2.0 ]
3'UTR of PTEN
(miRNA target sites are highlighted)
>PTEN|NM_0003|3'UTR
   1 TGAATTTTTTTTTATCAAGAGGGATAAAACACCATGAAAATAAACTTGAATAAACTGAAAATGGACCTTTTTTTTTTTAA
  81 TGGCAATAGGACATTGTGTCAGATTACCAGTTATAGGAACAATTCTCTTTTCCTGACCAATCTTGTTTTACCCTATACAT
 161 CCACAGGGTTTTGACACTTGTTGTCCAGTTGAAAAAAGGTTGTGTAGCTGTGTCATGTATATACCTTTTTGTGTCAAAAG
 241 GACATTTAAAATTCAATTAGGATTAATAAAGATGGCACTTTCCCGTTTTATTCCAGTTTTATAAAAAGTGGAGACAGACT
 321 GATGTGTATACGTAGGAATTTTTTCCTTTTGTGTTCTGTCACCAACTGAAGTGGCTAAAGAGCTTTGTGATATACTGGTT
 401 CACATCCTACCCCTTTGCACTTGTGGCAACAGATAAGTTTGCAGTTGGCTAAGAGAGGTTTCCGAAGGGTTTTGCTACAT
 481 TCTAATGCATGTATTCGGGTTAGGGGAATGGAGGGAATGCTCAGAAAGGAAATAATTTTATGCTGGACTCTGGACCATAT
 561 ACCATCTCCAGCTATTTACACACACCTTTCTTTAGCATGCTACAGTTATTAATCTGGACATTCGAGGAATTGGCCGCTGT
 641 CACTGCTTGTTGTTTGCGCATTTTTTTTTAAAGCATATTGGTGCTAGAAAAGGCAGCTAAAGGAAGTGAATCTGTATTGG
 721 GGTACAGGAATGAACCTTCTGCAACATCTTAAGATCCACAAATGAAGGGATATAAAAATAATGTCATAGGTAAGAAACAC
 801 AGCAACAATGACTTAACCATATAAATGTGGAGGCTATCAACAAAGAATGGGCTTGAAACATTATAAAAATTGACAATGAT
 881 TTATTAAATATGTTTTCTCAATTGTAACGACTTCTCCATCTCCTGTGTAATCAAGGCCAGTGCTAAAATTCAGATGCTGT
 961 TAGTACCTACATCAGTCAACAACTTACACTTATTTTACTAGTTTTCAATCATAATACCTGCTGTGGATGCTTCATGTGCT
1041 GCCTGCAAGCTTCTTTTTTCTCATTAAATATAAAATATTTTGTAATGCTGCACAGAAATTTTCAATTTGAGATTCTACAG
1121 TAAGCGTTTTTTTTCTTTGAAGATTTATGATGCACTTATTCAATAGCTGTCAGCCGTTCCACCCTTTTGACCTTACACAT
1201 TCTATTACAATGAATTTTGCAGTTTTGCACATTTTTTAAATGTCATTAACTGTTAGGGAATTTTACTTGAATACTGAATA
1281 CATATAATGTTTATATTAAAAAGGACATTTGTGTTAAAAAGGAAATTAGAGTTGCAGTAAACTTTCAATGCTGCACACAA
1361 AAAAAAGACATTTGATTTTTCAGTAGAAATTGTCCTACATGTGCTTTATTGATTTGCTATTGAAAGAATAGGGTTTTTTT
1441 TTTTTTTTTTTTTTTTTTTTTTAAATGTGCAGTGTTGAATCATTTCTTCATAGTGCTCCCCCGAGTTGGGACTAGGGCTT
1521 CAATTTCACTTCTTAAAAAAAATCATCATATATTTGATATGCCCAGACTGCATACGATTTTAAGCGGAGTACAACTACTA
1601 TTGTAAAGCTAATGTGAAGATATTATTAAAAAGGTTTTTTTTTCCAGAAATTTGGTGTCTTCAAATTATACCTTCACCTT
1681 GACATTTGAATATCCAGCCATTTTGTTTCTTAATGGTATAAAATTCCATTTTCAATAACTTATTGGTGCTGAAATTGTTC
1761 ACTAGCTGTGGTCTGACCTAGTTAATTTACAAATACAGATTGAATAGGACCTACTAGAGCAGCATTTATAGAGTTTGATG
1841 GCAAATAGATTAGGCAGAACTTCATCTAAAATATTCTTAGTAAATAATGTTGACACGTTTTCCATACCTTGTCAGTTTCA
1921 TTCAACAATTTTTAAATTTTTAACAAAGCTCTTAGGATTTACACATTTATATTTAAACATTGATATATAGAGTATTGATT
2001 GATTGCTCATAAGTTAAATTGGTAAAGTTAGAGACAACTATTCTAACACCTCACCATTGAAATTTATATGCCACCTTGTC
2081 TTTCATAAAAGCTGAAAATTGTTACCTAAAATGAAAATCAACTTCATGTTTTGAAGATAGTTATAAATATTGTTCTTTGT
2161 TACAATTTCGGGCACCGCATATTAAAACGTAACTTTATTGTTCCAATATGTAACATGGAGGGCCAGGTCATAAATAATGA
2241 CATTATAATGGGCTTTTGCACTGTTATTATTTTTCCTTTGGAATGTGAAGGTCTGAATGAGGGTTTTGATTTTGAATGTT
2321 TCAATGTTTTTGAGAAGCCTTGCTTACATTTTATGGTGTAGTCATTGGAAATGGAAAAATGGCATTATATATATTATATA
2401 TATAAATATATATTATACATACTCTCCTTACTTTATTTCAGTTACCATCCCCATAGAATTTGACAAGAATTGCTATGACT
2481 GAAAGGTTTTCGAGTCCTAATTAAAACTTTATTTATGGCAGTATTCATAATTAGCCTGAAATGCATTCTGTAGGTAATCT
2561 CTGAGTTTCTGGAATATTTTCTTAGACTTTTTGGATGTGCAGCAGCTTACATGTCTGAAGTTACTTGAAGGCATCACTTT
2641 TAAGAAAGCTTACAGTTGGGCCCTGTACCATCCCAAGTCCTTTGTAGCTCCTCTTGAACATGTTTGCCATACTTTTAAAA
2721 GGGTAGTTGAATAAATAGCATCACCATTCTTTGCTGTGGCACAGGTTATAAACTTAAGTGGAGTTTACCGGCAGCATCAA
2801 ATGTTTCAGCTTTAAAAAATAAAAGTAGGGTACAAGTTTAATGTTTAGTTCTAGAAATTTTGTGCAATATGTTCATAACG
2881 ATGGCTGTGGTTGCCACAAAGTGCCTCGTTTACCTTTAAATACTGTTAATGTGTCATGCATGCAGATGGAAGGGGTGGAA
2961 CTGTGCACTAAAGTGGGGGCTTTAACTGTAGTATTTGGCAGAGTTGCCTTCTACCTGCCAGTTCAAAAGTTCAACCTGTT
3041 TTCATATAGAATATATATACTAAAAAATTTCAGTCTGTTAAACAGCCTTACTCTGATTCAGCCTCTTCAGATACTCTTGT
3121 GCTGTGCAGCAGTGGCTCTGTGTGTAAATGCTATGCACTGAGGATACACAAAAATACCAATATGATGTGTACAGGATAAT
3201 GCCTCATCCCAATCAGATGTCCATTTGTTATTGTGTTTGTTAACAACCCTTTATCTCTTAGTGTTATAAACTCCACTTAA
3281 AACTGATTAAAGTCTCATTCTTGTCAAAAAAAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors  Predicted by miRanda
miRNA-target interactions (Predicted by miRanda)
IDDuplex structurePositionScoreMFE
1
miRNA  3' gaUGGACGUGA-UAUU-----CGUGAAAu 5'
            |:: | |:| ||||     ||||||| 
Target 5' caATTAGGATTAATAAAGATGGCACTTTc 3'
254 - 282 153.00 -6.60
2
miRNA  3' gaUGGACGUGAUAUUCGUGAAAu 5'
            :|:||:  | |: |||:||| 
Target 5' ctGCTTGTTGTTTGCGCATTTTt 3'
643 - 665 141.00 -13.00
3
miRNA  3' gauGGACGU---GAUAUU-CGUGAAau 5'
             ::|| |   :|||:| ||||||  
Target 5' ttcTTTGAAGATTTATGATGCACTTat 3'
1133 - 1159 136.00 -9.20
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target hsa-miR-20a-5p :: PTEN    [ Functional MTI ]
Validation Method Luciferase reporter assay , qRT-PCR , Western blot , Other
Conditions HCT116
Location of target site 3'UTR
Tools used in this research RNA22 , TargetScan
Original Description (Extracted from the article) ... A luciferase reporter, when fused with the wild-type human PTEN 3`UTR, was significantly repressed by overexpression of miR-19b, but not by miR-17, miR-18a,miR-20a ...

- Olive, V. Bennett, M. J. Walker, J. C. Ma, et al., 2009, Genes Dev.

Article - Olive, V. Bennett, M. J. Walker, J. C. Ma, et al.
- Genes Dev, 2009
Recent studies have revealed the importance of multiple microRNAs (miRNAs) in promoting tumorigenesis, among which mir-17-92/Oncomir-1 exhibits potent oncogenic activity. Genomic amplification and elevated expression of mir-17-92 occur in several human B-cell lymphomas, and enforced mir-17-92 expression in mice cooperates with c-myc to promote the formation of B-cell lymphomas. Unlike classic protein-coding oncogenes, mir-17-92 has an unconventional gene structure, where one primary transcript yields six individual miRNAs. Here, we functionally dissected the individual components of mir-17-92 by assaying their tumorigenic potential in vivo. Using the Emu-myc model of mouse B-cell lymphoma, we identified miR-19 as the key oncogenic component of mir-17-92, both necessary and sufficient for promoting c-myc-induced lymphomagenesis by repressing apoptosis. The oncogenic activity of miR-19 is at least in part due to its repression of the tumor suppressor Pten. Consistently, miR-19 activates the Akt-mTOR (mammalian target of rapamycin) pathway, thereby functionally antagonizing Pten to promote cell survival. Our findings reveal the essential role of miR-19 in mediating the oncogenic activity of mir-17-92, and implicate the functional diversity of mir-17-92 components as the molecular basis for its pleiotropic effects during tumorigenesis.
LinkOut: [PMID: 20008935]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target hsa-miR-20a-5p :: PTEN    [ Functional MTI ]
Validation Method Luciferase reporter assay
Conditions HEK293T
Location of target site 3'UTR
Tools used in this research DAVID , DIANA-microT , miRanda , mirGen , PicTar , TargetScan , TargetScanS
Original Description (Extracted from the article) ... Fig. 2A demonstrates that, with the exception of E2F3 and MAPK9, miR-17 significantly influences all target genes tested irrespective of an activating or inhibiting function in cell proliferation. Among the pro-proliferative targets, the strongest effects were seen for CCND1 (appr. 47% reduction in normalized Firefly activity) and E2F1 (29% reduction). RBL2 and CDKN1A showed the strongest reductions in activity among the set of anti-proliferative proteins tested (52% and 30% respectively). As seen in Figs. 2B and 2C, miR- 20a and miR-106b showed highly similar behavior compared to miR-17 regarding significant Firefly activity reductions and relative influences between the analyzed target genes. ...

- Trompeter, H. I. Abbad, H. Iwaniuk, K. M. et al., 2011, PLoS One.

Article - Trompeter, H. I. Abbad, H. Iwaniuk, K. M. et al.
- PLoS One, 2011
BACKGROUND: MicroRNAs are short ( approximately 22 nt) non-coding regulatory RNAs that control gene expression at the post-transcriptional level. Here the functional impact of microRNAs on cell cycle arrest during neuronal lineage differentiation of unrestricted somatic stem cells from human cord blood (USSC) was analyzed. METHODOLOGY/PRINCIPAL FINDINGS: Expression profiling revealed downregulation of microRNAs miR-17, -20a, and -106b in USSC differentiated into neuronal lineage but not in USSC differentiated into osteogenic lineage. Transfection experiments followed by Ki67 immunostainings demonstrated that each of these microRNAs was able to promote proliferation of native USSC and to prevent in part cell cycle arrest during neuronal lineage differentiation of USSC. Bioinformatic target gene predictions followed by experimental target gene validations revealed that miR-17, -20a, and -106b act in a common manner by downregulating an overlapping set of target genes mostly involved in regulation and execution of G(1)/S transition. Pro-proliferative target genes cyclinD1 (CCND1) and E2F1 as well as anti-proliferative targets CDKN1A (p21), PTEN, RB1, RBL1 (p107), RBL2 (p130) were shown as common targets for miR-17, -20a, and -106b. Furthermore, these microRNAs also downregulate WEE1 which is involved in G(2)/M transition. Most strikingly, miR-17, -20a, and -106b were found to promote cell proliferation by increasing the intracellular activity of E2F transcription factors, despite the fact that miR-17, -20a, and -106b directly target the transcripts that encode for this protein family. CONCLUSIONS/SIGNIFICANCE: Mir-17, -20a, and -106b downregulate a common set of pro- and anti-proliferative target genes to impact cell cycle progression of USSC and increase intracellular activity of E2F transcription factors to govern G(1)/S transition.
LinkOut: [PMID: 21283765]
MiRNA-Target Expression Profile:

 
MiRNA-Target Interaction Network:
Strong evidence (reporter assay, western blot, qRT-PCR or qPCR)
Other evidence
193 hsa-miR-20a-5p Target Genes:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT000002 HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 4 2
MIRT000178 TCEAL1 transcription elongation factor A (SII)-like 1 1 1
MIRT000179 CCND1 cyclin D1 4 3
MIRT000180 E2F1 E2F transcription factor 1 3 5
MIRT000181 BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 4 1
MIRT000597 CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 4 3
MIRT001785 TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 5 4
MIRT003010 MAP3K12 mitogen-activated protein kinase kinase kinase 12 2 1
MIRT003011 BCL2 B-cell CLL/lymphoma 2 2 1
MIRT003012 MEF2D myocyte enhancer factor 2D 2 1
MIRT003369 PTEN phosphatase and tensin homolog 4 2
MIRT003382 APP amyloid beta (A4) precursor protein 4 2
MIRT003742 RUNX1 runt-related transcription factor 1 4 1
MIRT003903 NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 2 1
MIRT004450 VEGFA vascular endothelial growth factor A 2 1
MIRT004570 BCL2L11 BCL2-like 11 (apoptosis facilitator) 1 2
MIRT004711 MUC17 mucin 17, cell surface associated 3 1
MIRT005289 MYC v-myc myelocytomatosis viral oncogene homolog (avian) 2 1
MIRT005481 BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 4 2
MIRT005627 THBS1 thrombospondin 1 3 1
MIRT005631 SMAD4 SMAD family member 4 2 1
MIRT005854 CCND2 cyclin D2 1 1
MIRT005855 E2F3 E2F transcription factor 3 1 1
MIRT005856 MAPK9 mitogen-activated protein kinase 9 1 1
MIRT005857 RB1 retinoblastoma 1 1 1
MIRT005858 RBL1 retinoblastoma-like 1 (p107) 1 1
MIRT005859 RBL2 retinoblastoma-like 2 (p130) 2 2
MIRT005860 WEE1 WEE1 homolog (S. pombe) 1 1
MIRT006178 IRF2 interferon regulatory factor 2 4 1
MIRT006180 KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 4 1
MIRT006289 EGLN3 egl nine homolog 3 (C. elegans) 2 1
MIRT006612 Tgfbr2 transforming growth factor, beta receptor II 3 1
MIRT006754 PPARG peroxisome proliferator-activated receptor gamma 1 1
MIRT006755 BAMBI BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) 1 1
MIRT006756 CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 1 1
MIRT006772 MAP2K3 mitogen-activated protein kinase kinase 3 1 1
MIRT007002 PURA purine-rich element binding protein A 1 1
MIRT031080 IL8 interleukin 8 1 1
MIRT031081 JAK1 Janus kinase 1 1 1
MIRT031082 ARHGAP12 Rho GTPase activating protein 12 1 1
MIRT031083 TSG101 tumor susceptibility gene 101 1 1
MIRT035531 SIRPA signal-regulatory protein alpha 1 1
MIRT050476 PHF8 PHD finger protein 8 1 1
MIRT050477 GPATCH11 coiled-coil domain containing 75 1 1
MIRT050478 RPRD1A regulation of nuclear pre-mRNA domain containing 1A 1 1
MIRT050479 ATP8B2 ATPase, class I, type 8B, member 2 1 1
MIRT050480 PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 1 1
MIRT050481 INSIG1 insulin induced gene 1 1 1
MIRT050482 RTN2 reticulon 2 1 1
MIRT050483 TCEA1 transcription elongation factor A (SII), 1 1 1
MIRT050484 PLEKHM3 pleckstrin homology domain containing, family M, member 3 1 1
MIRT050485 RPS10 ribosomal protein S10 1 1
MIRT050486 ALDH18A1 aldehyde dehydrogenase 18 family, member A1 1 1
MIRT050487 UEVLD UEV and lactate/malate dehyrogenase domains 1 1
MIRT050488 FGF7 fibroblast growth factor 7 (keratinocyte growth factor) 1 1
MIRT050489 SSRP1 structure specific recognition protein 1 1 1
MIRT050490 COX5A cytochrome c oxidase subunit Va 1 1
MIRT050491 AGO1 eukaryotic translation initiation factor 2C, 1 1 1
MIRT050492 KIAA0100 KIAA0100 1 1
MIRT050493 FHL3 four and a half LIM domains 3 1 1
MIRT050494 GDI2 GDP dissociation inhibitor 2 1 1
MIRT050495 INTS3 integrator complex subunit 3 1 1
MIRT050496 HMG20A high-mobility group 20A 1 1
MIRT050497 APOA1BP apolipoprotein A-I binding protein 1 1
MIRT050498 PRKD3 protein kinase D3 1 1
MIRT050499 AP3S2 adaptor-related protein complex 3, sigma 2 subunit 1 1
MIRT050500 PCNXL4 chromosome 14 open reading frame 135 1 1
MIRT050501 IKZF5 IKAROS family zinc finger 5 (Pegasus) 1 1
MIRT050502 TMEM97 transmembrane protein 97 1 1
MIRT050503 ATP6 ATP synthase F0 subunit 6 1 1
MIRT050504 RPA2 replication protein A2, 32kDa 1 1
MIRT050505 PHYH phytanoyl-CoA 2-hydroxylase 1 1
MIRT050506 KIF2C kinesin family member 2C 1 1
MIRT050507 DDX5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 1 1
MIRT050508 DTX2 deltex homolog 2 (Drosophila) 1 1
MIRT050509 MPHOSPH8 M-phase phosphoprotein 8 1 1
MIRT050510 HAUS2 HAUS augmin-like complex, subunit 2 1 1
MIRT050511 ZNF331 zinc finger protein 331 1 1
MIRT050512 PPP6R3 SAPS domain family, member 3 1 1
MIRT050513 METTL22 chromosome 16 open reading frame 68 1 1
MIRT050514 PPAN peter pan homolog (Drosophila) 1 1
MIRT050515 FBL fibrillarin 1 1
MIRT050516 RPL31 ribosomal protein L31 1 1
MIRT050517 SEPT2 septin 2 1 1
MIRT050518 TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 1 1
MIRT050519 NCOR2 nuclear receptor corepressor 2 1 1
MIRT050520 PSD3 pleckstrin and Sec7 domain containing 3 1 1
MIRT050521 AP3D1 adaptor-related protein complex 3, delta 1 subunit 1 1
MIRT050522 TBC1D15 TBC1 domain family, member 15 1 1
MIRT050523 DPY19L4 dpy-19-like 4 (C. elegans) 1 1
MIRT050524 PTPN23 protein tyrosine phosphatase, non-receptor type 23 1 1
MIRT050525 C11orf68 chromosome 11 open reading frame 68 1 1
MIRT050526 CTR9 Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 1 1
MIRT050527 PAIP1 poly(A) binding protein interacting protein 1 1 1
MIRT050528 L2HGDH L-2-hydroxyglutarate dehydrogenase 1 1
MIRT050529 CDT1 chromatin licensing and DNA replication factor 1 1 1
MIRT050530 RPL30 ribosomal protein L30 1 1
MIRT050531 MRS2 MRS2 magnesium homeostasis factor homolog (S. cerevisiae) 1 1
MIRT050532 TMX4 thioredoxin-related transmembrane protein 4 1 1
MIRT050533 LAMTOR1 chromosome 11 open reading frame 59 1 1
MIRT050534 LPHN3 latrophilin 3 1 1
MIRT050535 RBM10 RNA binding motif protein 10 1 1
MIRT050536 EMR2 egf-like module containing, mucin-like, hormone receptor-like 2 1 1
MIRT050537 FBXO3 F-box protein 3 1 1
MIRT050538 MLXIP MLX interacting protein 1 1
MIRT050539 RNGTT RNA guanylyltransferase and 5'-phosphatase 1 1
MIRT050540 MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 1 1
MIRT050541 DLC1 deleted in liver cancer 1 1 1
MIRT050542 NUP214 nucleoporin 214kDa 1 1
MIRT050543 PAQR5 progestin and adipoQ receptor family member V 1 1
MIRT050544 BTBD2 BTB (POZ) domain containing 2 1 1
MIRT050545 XYLT2 xylosyltransferase II 1 1
MIRT050546 ZNF398 zinc finger protein 398 1 1
MIRT050547 CEP120 centrosomal protein 120kDa 1 1
MIRT050548 IL17RC interleukin 17 receptor C 1 1
MIRT050549 UBE2C ubiquitin-conjugating enzyme E2C 1 1
MIRT050550 PGK1 phosphoglycerate kinase 1 1 1
MIRT050551 ORMDL3 ORM1-like 3 (S. cerevisiae) 1 1
MIRT050552 TUBB tubulin, beta 1 1
MIRT050553 TDRD3 tudor domain containing 3 1 1
MIRT050554 DLG5 discs, large homolog 5 (Drosophila) 1 1
MIRT050555 VEZF1 vascular endothelial zinc finger 1 1 1
MIRT050556 CCDC88C coiled-coil domain containing 88C 1 1
MIRT050557 USP10 ubiquitin specific peptidase 10 1 1
MIRT050558 KIAA1191 KIAA1191 1 1
MIRT050559 STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1 1
MIRT050560 GATA6 GATA binding protein 6 1 1
MIRT050561 RPL18A ribosomal protein L18a 1 1
MIRT050562 TMEM66 transmembrane protein 66 1 1
MIRT050563 ARL9 ADP-ribosylation factor-like 9 1 1
MIRT050564 CTSA cathepsin A 1 1
MIRT050565 ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 1 1
MIRT050566 MRPL13 mitochondrial ribosomal protein L13 1 1
MIRT050567 MAN1C1 mannosidase, alpha, class 1C, member 1 1 1
MIRT050568 AGO4 eukaryotic translation initiation factor 2C, 4 1 1
MIRT050569 BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 1 1
MIRT050570 RFC3 replication factor C (activator 1) 3, 38kDa 1 1
MIRT050571 ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 1 1
MIRT050572 GPN2 GPN-loop GTPase 2 1 1
MIRT050573 LDHB lactate dehydrogenase B 1 1
MIRT050574 PTPRS protein tyrosine phosphatase, receptor type, S 1 1
MIRT050575 PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 1 1
MIRT050576 CDK16 cyclin-dependent kinase 16 1 1
MIRT050577 WBP4 WW domain binding protein 4 (formin binding protein 21) 1 1
MIRT050578 CCNB1 cyclin B1 1 1
MIRT050579 POGZ pogo transposable element with ZNF domain 1 1
MIRT050580 KLHL15 kelch-like 15 (Drosophila) 1 1
MIRT050581 RTFDC1 chromosome 20 open reading frame 43 1 1
MIRT050582 FLNA filamin A, alpha 1 1
MIRT050583 PLXNA1 plexin A1 1 1
MIRT050584 ADSS adenylosuccinate synthase 1 1
MIRT050585 MANEAL mannosidase, endo-alpha-like 1 1
MIRT050586 NUP188 nucleoporin 188kDa 1 1
MIRT050587 ECI1 dodecenoyl-CoA isomerase 1 1
MIRT050588 NCOA3 nuclear receptor coactivator 3 1 1
MIRT050589 MORF4L2 mortality factor 4 like 2 1 1
MIRT050590 ATL3 atlastin GTPase 3 1 1
MIRT050591 FOXJ3 forkhead box J3 1 1
MIRT050592 PRRC2C HLA-B associated transcript 2-like 2 1 1
MIRT050593 RPL21 ribosomal protein L21 1 1
MIRT050594 SELENBP1 selenium binding protein 1 1 1
MIRT050595 YBX1 Y box binding protein 1 1 1
MIRT050596 B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 1 1
MIRT050597 PYGB phosphorylase, glycogen; brain 1 1
MIRT050598 AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 1 1
MIRT050599 C9orf78 chromosome 9 open reading frame 78 1 1
MIRT050600 STIL SCL/TAL1 interrupting locus 1 1
MIRT050601 CDK19 cyclin-dependent kinase 19 1 1
MIRT050602 KDM4D lysine (K)-specific demethylase 4D 1 1
MIRT050603 UQCRC1 ubiquinol-cytochrome c reductase core protein I 1 1
MIRT050604 RUFY2 RUN and FYVE domain containing 2 1 1
MIRT050605 RPS27 ribosomal protein S27 1 1
MIRT050606 BTN3A1 butyrophilin, subfamily 3, member A1 1 1
MIRT050607 PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 1 1
MIRT050608 ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 1 1
MIRT050609 NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 1 1
MIRT050610 NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 1 1
MIRT050611 SLC25A28 solute carrier family 25, member 28 1 1
MIRT050612 NAP1L1 nucleosome assembly protein 1-like 1 1 1
MIRT050613 PHC1 polyhomeotic homolog 1 (Drosophila) 1 1
MIRT050614 ZNF706 zinc finger protein 706 1 1
MIRT050615 CCDC47 coiled-coil domain containing 47 1 1
MIRT050616 ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 1 1
MIRT050617 EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 1 1
MIRT050618 MAGOHB mago-nashi homolog B (Drosophila) 1 1
MIRT050619 ZNF598 zinc finger protein 598 1 1
MIRT050620 LEPREL4 synaptonemal complex protein SC65 1 1
MIRT050621 CERS2 LAG1 homolog, ceramide synthase 2 1 1
MIRT050622 LYPD6 LY6/PLAUR domain containing 6 1 1
MIRT050623 HEXIM1 hexamethylene bis-acetamide inducible 1 1 1
MIRT050624 WAC WW domain containing adaptor with coiled-coil 1 1
MIRT050625 ZNFX1 zinc finger, NFX1-type containing 1 1 1
MIRT050626 RBM12B RNA binding motif protein 12B 1 1