Accession ID: MIRT006924 [miRNA, hsa-miR-10b-5p :: NOTCH1, target gene]
pre-miRNA Information
pre-miRNA ID hsa-mir-10bLinkOut: [miRBase ]
Synonyms MIRN10B, hsa-mir-10b, miRNA10B, mir-10b, MIR10B
Description Homo sapiens miR-10b stem-loop
Comment This human miRNA was predicted by computational methods using conservation with mouse and Fugu rubripes sequences .
2nd Structure of pre-miRNA
Disease
Mature miRNA Information
Mature miRNA hsa-miR-10b-5p
Mature Sequence 27| UACCCUGUAGAACCGAAUUUGUG |49
Evidence Experimental
Experiments Cloned
Putative hsa-miR-10b-5p Targets LinkOut: [ TargetScanS 5.1 | MicroCosm | microRNA.org | miRecords | miRDB | miRo | miRNAMap 2.0 ]
Gene Information
Gene Symbol NOTCH1 LinkOut: [ Entrez Gene | BioGPS | Wikipedia | iHop ]
Synonyms TAN1, hN1
Description notch 1
Transcript NM_017617    LinkOut: [ RefSeq ]
Expression LinkOut: [ BioGPS ]
Putative miRNA Targets on NOTCH1 LinkOut: [ TargetScan 5.1 | MicroCosm | miRNAMap 2.0 ]
3'UTR of NOTCH1
(miRNA target sites are highlighted)
>NOTCH1|NM_017617|3'UTR
   1 ACGGCGCGCCCCACGAGACCCCGGCTTCCTTTCCCAAGCCTTCGGGCGTCTGTGTGCGCTCTGTGGATGCCAGGGCCGAC
  81 CAGAGGAGCCTTTTTAAAACACATGTTTTTATACAAAATAAGAACGAGGATTTTAATTTTTTTTAGTATTTATTTATGTA
 161 CTTTTATTTTACACAGAAACACTGCCTTTTTATTTATATGTACTGTTTTATCTGGCCCCAGGTAGAAACTTTTATCTATT
 241 CTGAGAAAACAAGCAAGTTCTGAGAGCCAGGGTTTTCCTACGTAGGATGAAAAGATTCTTCTGTGTTTATAAAATATAAA
 321 CAAAGATTCATGATTTATAAATGCCATTTATTTATTGATTCCTTTTTTCAAAATCCAAAAAGAAATGATGTTGGAGAAGG
 401 GAAGTTGAACGAGCATAGTCCAAAAAGCTCCTGGGGCGTCCAGGCCGCGCCCTTTCCCCGACGCCCACCCAACCCCAAGC
 481 CAGCCCGGCCGCTCCACCAGCATCACCTGCCTGTTAGGAGAAGCTGCATCCAGAGGCAAACGGAGGCAAAGCTGGCTCAC
 561 CTTCCGCACGCGGATTAATTTGCATCTGAAATAGGAAACAAGTGAAAGCATATGGGTTAGATGTTGCCATGTGTTTTAGA
 641 TGGTTTCTTGCAAGCATGCTTGTGAAAATGTGTTCTCGGAGTGTGTATGCCAAGAGTGCACCCATGGTACCAATCATGAA
 721 TCTTTGTTTCAGGTTCAGTATTATGTAGTTGTTCGTTGGTTATACAAGTTCTTGGTCCCTCCAGAACCACCCCGGCCCCC
 801 TGCCCGTTCTTGAAATGTAGGCATCATGCATGTCAAACATGAGATGTGTGGACTGTGGCACTTGCCTGGGTCACACACGG
 881 AGGCATCCTACCCTTTTCTGGGGAAAGACACTGCCTGGGCTGACCCCGGTGGCGGCCCCAGCACCTCAGCCTGCACAGTG
 961 TCCCCCAGGTTCCGAAGAAGATGCTCCAGCAACACAGCCTGGGCCCCAGCTCGCGGGACCCGACCCCCCGTGGGCTCCCG
1041 TGTTTTGTAGGAGACTTGCCAGAGCCGGGCACATTGAGCTGTGCAACGCCGTGGGCTGCGTCCTTTGGTCCTGTCCCCGC
1121 AGCCCTGGCAGGGGGCATGCGGTCGGGCAGGGGCTGGAGGGAGGCGGGGGCTGCCCTTGGGCCACCCCTCCTAGTTTGGG
1201 AGGAGCAGATTTTTGCAATACCAAGTATAGCCTATGGCAGAAAAAATGTCTGTAAATATGTTTTTAAAGGTGGATTTTGT
1281 TTAAAAAATCTTAATGAATGAGTCTGTTGTGTGTCATGCCAGTGAGGGACGTCAGACTTGGCTCAGCTCGGGGAGCCTTA
1361 GCCGCCCATGCACTGGGGACGCTCCGCTGCCGTGCCGCCTGCACTCCTCAGGGCAGCCTCCCCCGGCTCTACGGGGGCCG
1441 CGTGGTGCCATCCCCAGGGGGCATGACCAGATGCGTCCCAAGATGTTGATTTTTACTGTGTTTTATAAAATAGAGTGTAG
1521 TTTACAGAAAAAGACTTTAAAAGTGATCTACATGAGGAACTGTAGATGATGTATTTTTTTCATCTTTTTTGTTAACTGAT
1601 TTGCAATAAAAATGATACTGATGGTGA
Target sites Provided by authors  Predicted by miRanda
miRNA-target interactions (Predicted by miRanda)
IDDuplex structurePositionScoreMFE
1
miRNA  3' guguuuaaGCCAAGAUGUCCCau 5'
                  ||| |||||:|||  
Target 5' gcctccccCGGCTCTACGGGGgc 3'
1416 - 1438 131.00 -19.70
2
miRNA  3' guGUUUAAGCCAAGAUGUCCCAu 5'
            |||:||| |     |||||| 
Target 5' agCAAGTTCTGAGAGCCAGGGTt 3'
252 - 274 129.00 -15.44
3
miRNA  3' guguuUAAGCCAAGAUGUCCCau 5'
               || ||||   :|||||  
Target 5' ggggcATGCGGTCGGGCAGGGgc 3'
1132 - 1154 122.00 -16.10
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target hsa-miR-10b-5p :: NOTCH1    [ Functional MTI ]
Validation Method Luciferase reporter assay
Conditions U87-2M1
Original Description (Extracted from the article) ... miRNA-10b’s target genes HOXD10, NOTCH1, TP53 and PAX6 regulate invasiveness of U87-2M1 glioma cells ...

- Lin, J. Teo, S. Lam, D. H. Jeyaseelan, K. Wang, S., 2012, Cell Death Dis.

Article - Lin, J. Teo, S. Lam, D. H. Jeyaseelan, K. Wang, S.
- Cell Death Dis, 2012
Glioblastoma multiforme (GBM) is a heterogeneous disease despite its seemingly uniform pathology. Deconvolution of The Cancer Genome Atlas's GBM gene expression data has unveiled the existence of distinct gene expression signature underlying discrete GBM subtypes. Recent conflicting findings proposed that microRNA (miRNA)-10b exclusively regulates glioma growth or invasion but not both. We showed that silencing of miRNA-10b by baculoviral decoy vectors in a glioma cell line resembling the mesenchymal subtype of GBM reduces its growth, invasion and angiogenesis while promoting apoptosis in vitro. In an orthotopic human glioma mouse model, inhibition of miRNA-10b diminishes the invasiveness, angiogenicity and growth of the mesenchymal subtype-like glioma cells in the brain and significantly prolonged survival of glioma-bearing mice. We demonstrated that the pleiotropic nature of miRNA-10b was due to its suppression of multiple tumor suppressors, including TP53, FOXO3, CYLD, PAX6, PTCH1, HOXD10 and NOTCH1. In particular, siRNA-mediated knockdown experiments identified TP53, PAX6, NOTCH1 and HOXD10 as invasion regulatory genes in our mesenchymal subtype-like glioma cells. By interrogating the REMBRANDT, we noted that dysregulation of many direct targets of miRNA-10b was associated with significantly poorer patient survival. Thus, our study uncovers a novel role for miRNA-10b in regulating angiogenesis and suggests that miRNA-10b may be a pleiotropic regulator of gliomagenesis.
LinkOut: [PMID: 23034333]
MiRNA-Target Expression Profile:

 
MiRNA-Target Expression Profile(TCGA):

 
MiRNA-Target Interaction Network:
Strong evidence (reporter assay, western blot, qRT-PCR or qPCR)
Other evidence
296 hsa-miR-10b-5p Target Genes:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT002021 HOXD10 homeobox D10 4 11
MIRT003216 KLF4 Kruppel-like factor 4 (gut) 4 3
MIRT005068 PPARA peroxisome proliferator-activated receptor alpha 4 1
MIRT005455 NCOR2 nuclear receptor corepressor 2 3 2
MIRT005504 NF1 neurofibromin 1 4 1
MIRT006294 PIEZO1 piezo-type mechanosensitive ion channel component 1 1 1
MIRT006366 BCL2L11 BCL2-like 11 (apoptosis facilitator) 3 3
MIRT006367 TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 3 2
MIRT006368 CDKN2A cyclin-dependent kinase inhibitor 2A 3 2
MIRT006369 CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 2 1
MIRT006538 TRA2B transformer 2 beta homolog (Drosophila) 2 2
MIRT006539 SRSF1 serine/arginine-rich splicing factor 1 1 1
MIRT006923 TP53 tumor protein p53 1 1
MIRT006924 NOTCH1 notch 1 1 1
MIRT006925 PAX6 paired box 6 1 1
MIRT007026 MAPRE1 microtubule-associated protein, RP/EB family, member 1 1 1
MIRT007072 SDC1 syndecan 1 1 3
MIRT025586 NR4A3 nuclear receptor subfamily 4, group A, member 3 1 1
MIRT025587 NRP2 neuropilin 2 1 1
MIRT047400 POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 1 1
MIRT047401 LEMD3 LEM domain containing 3 1 1
MIRT047402 EXTL3 exostoses (multiple)-like 3 1 1
MIRT047403 TXNDC16 thioredoxin domain containing 16 1 1
MIRT047404 STK33 serine/threonine kinase 33 1 1
MIRT047405 ZC3H18 zinc finger CCCH-type containing 18 1 1
MIRT047406 GBAS glioblastoma amplified sequence 1 1
MIRT047407 COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 1 1
MIRT047408 ADRA1B adrenoceptor alpha 1B 1 1
MIRT047409 RTKN2 rhotekin 2 1 1
MIRT047410 COL6A2 collagen, type VI, alpha 2 1 1
MIRT047411 ZNF318 zinc finger protein 318 1 1
MIRT047412 INHBA inhibin, beta A 1 1
MIRT047413 SYT11 synaptotagmin XI 1 1
MIRT047414 SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1 1
MIRT047415 IGSF1 immunoglobulin superfamily, member 1 1 1
MIRT047416 IPCEF1 interaction protein for cytohesin exchange factors 1 1 1
MIRT047417 PPP1R13B protein phosphatase 1, regulatory subunit 13B 1 1
MIRT047418 APLNR apelin receptor 1 1
MIRT047419 MSL3 male-specific lethal 3 homolog (Drosophila) 1 1
MIRT047420 SLC25A30 solute carrier family 25, member 30 1 1
MIRT047421 CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3 1 1
MIRT047422 XPO7 exportin 7 1 1
MIRT047423 STT3A STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) 1 1
MIRT047424 UROD uroporphyrinogen decarboxylase 1 1
MIRT047425 SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 1 1
MIRT047426 GLB1L3 galactosidase, beta 1-like 3 1 1
MIRT047427 FEM1B fem-1 homolog b (C. elegans) 1 1
MIRT047428 CLPTM1 cleft lip and palate associated transmembrane protein 1 1 1
MIRT047429 FAM13A family with sequence similarity 13, member A 1 1
MIRT047430 HSPA1B heat shock 70kDa protein 1B 1 1
MIRT047431 CSNK2A1 casein kinase 2, alpha 1 polypeptide 1 2
MIRT047432 KIF21A kinesin family member 21A 1 1
MIRT047433 HK1 hexokinase 1 1 1
MIRT047434 EIF1 eukaryotic translation initiation factor 1 1 1
MIRT047435 AP3M1 adaptor-related protein complex 3, mu 1 subunit 1 1
MIRT047436 HIST1H2AL histone cluster 1, H2al 1 1
MIRT047437 ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 1 1
MIRT047438 RUNDC3B RUN domain containing 3B 1 1
MIRT047439 PRPF8 PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) 1 1
MIRT047440 ND6 NADH dehydrogenase, subunit 6 (complex I) 1 1
MIRT047441 SCMH1 sex comb on midleg homolog 1 (Drosophila) 1 1
MIRT047442 LRRC59 leucine rich repeat containing 59 1 1
MIRT047443 ERLIN1 ER lipid raft associated 1 1 1
MIRT047444 FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 1 1
MIRT047445 CDK2 cyclin-dependent kinase 2 1 1
MIRT047446 DDHD2 DDHD domain containing 2 1 1
MIRT047447 PTPRT protein tyrosine phosphatase, receptor type, T 1 1
MIRT047448 UBE2Z ubiquitin-conjugating enzyme E2Z 1 1
MIRT047449 ORAI2 ORAI calcium release-activated calcium modulator 2 1 1
MIRT047450 ACLY ATP citrate lyase 1 1
MIRT047451 PARL presenilin associated, rhomboid-like 1 1
MIRT047452 DIAPH2 diaphanous homolog 2 (Drosophila) 1 1
MIRT047453 RPS9 ribosomal protein S9 1 1
MIRT047454 FASN fatty acid synthase 1 1
MIRT047455 ESYT1 extended synaptotagmin-like protein 1 1 1
MIRT047456 TENM3 teneurin transmembrane protein 3 1 1
MIRT047457 GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 1 1
MIRT047458 TUBA1B tubulin, alpha 1b 1 1
MIRT047459 CDK12 cyclin-dependent kinase 12 1 1
MIRT047460 PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 1 1
MIRT047461 RPS8 ribosomal protein S8 1 1
MIRT047462 ATG13 autophagy related 13 1 1
MIRT047463 PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1 1
MIRT047464 C9orf114 chromosome 9 open reading frame 114 1 1
MIRT047465 PLA2G4F phospholipase A2, group IVF 1 1
MIRT047466 USP3 ubiquitin specific peptidase 3 1 1
MIRT047467 SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 1 1
MIRT047468 DMWD dystrophia myotonica, WD repeat containing 1 1
MIRT047469 HNRNPF heterogeneous nuclear ribonucleoprotein F 1 1
MIRT047470 RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae) 1 1
MIRT047471 PFAS phosphoribosylformylglycinamidine synthase 1 1
MIRT047472 KBTBD6 kelch repeat and BTB (POZ) domain containing 6 1 1
MIRT047473 LAMC1 laminin, gamma 1 (formerly LAMB2) 1 1
MIRT047474 SURF6 surfeit 6 1 1
MIRT047475 GLOD4 glyoxalase domain containing 4 1 1
MIRT047476 PRMT7 protein arginine methyltransferase 7 1 1
MIRT047477 MSTO1 misato homolog 1 (Drosophila) 1 1
MIRT047478 NEK7 NIMA (never in mitosis gene a)-related kinase 7 1 1
MIRT047479 EPHA4 EPH receptor A4 1 1
MIRT047480 ACTG1 actin, gamma 1 1 1
MIRT047481 KIAA0100 KIAA0100 1 1
MIRT047482 TSPAN33 tetraspanin 33 1 1
MIRT047483 C6orf106 chromosome 6 open reading frame 106 1 1
MIRT047484 THUMPD1 THUMP domain containing 1 1 1
MIRT047485 DLAT dihydrolipoamide S-acetyltransferase 1 1
MIRT047486 LRP3 low density lipoprotein receptor-related protein 3 1 1
MIRT047487 AASDH aminoadipate-semialdehyde dehydrogenase 1 1
MIRT047488 SETD7 SET domain containing (lysine methyltransferase) 7 1 1
MIRT047489 RBM17 RNA binding motif protein 17 1 1
MIRT047490 GK glycerol kinase 1 1
MIRT047491 LMF2 lipase maturation factor 2 1 1
MIRT047492 CHPF2 chondroitin polymerizing factor 2 1 1
MIRT047493 CTBP1 C-terminal binding protein 1 1 1
MIRT047494 UHRF1 ubiquitin-like with PHD and ring finger domains 1 1 1
MIRT047495 WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1 1 1
MIRT047496 RALBP1 ralA binding protein 1 1 1
MIRT047497 NAP1L1 nucleosome assembly protein 1-like 1 1 1
MIRT047498 LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1 1
MIRT047499 NPTX1 neuronal pentraxin I 1 1
MIRT047500 PRRC2C proline-rich coiled-coil 2C 1 1
MIRT047501 PABPC1 poly(A) binding protein, cytoplasmic 1 1 1
MIRT047502 PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 1 1
MIRT047503 PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 1 1
MIRT047504 NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 1 1
MIRT053002 TPM1 tropomyosin 1 (alpha) 1 1
MIRT053003 PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 1 1
MIRT053593 TIAM1 T-cell lymphoma invasion and metastasis 1 3 1
MIRT054912 PTEN phosphatase and tensin homolog 2 2
MIRT056370 ZMYND11 zinc finger, MYND-type containing 11 0 1
MIRT057215 GATA3 GATA binding protein 3 0 1
MIRT071380 CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 1 3
MIRT076414 PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 1 1
MIRT093336 RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 1 1
MIRT097758 ARSK arylsulfatase family, member K 1 1
MIRT099598 ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 1 3
MIRT299202 CSRNP3 cysteine-serine-rich nuclear protein 3 1 1
MIRT309534 TRIM2 tripartite motif containing 2 1 2
MIRT437374 HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 3 1
MIRT437784 DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 1 1
MIRT439113 TCF19 transcription factor 19 0 1
MIRT439114 USP6 ubiquitin specific peptidase 6 (Tre-2 oncogene) 0 1
MIRT439115 TCF15 transcription factor 15 (basic helix-loop-helix) 1 2
MIRT439116 STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0 1
MIRT439117 SREBF1 sterol regulatory element binding transcription factor 1 0 1
MIRT439118 RARG retinoic acid receptor, gamma 0 1
MIRT439119 OLFM3 olfactomedin 3 0 1
MIRT439120 NUAK2 NUAK family, SNF1-like kinase, 2 0 1
MIRT439121 MYF5 myogenic factor 5 0 1
MIRT439122 NCOA6 nuclear receptor coactivator 6 0 1
MIRT439123 LYL1 lymphoblastic leukemia derived sequence 1 0 1
MIRT439124 HOXD1 homeobox D1 0 1
MIRT439125 HOXD11 homeobox D11 0 1
MIRT439126 HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0 1
MIRT439127 HHAT hedgehog acyltransferase 0 1
MIRT439128 DPF2 D4, zinc and double PHD fingers family 2 0 1
MIRT439129 FXR2 fragile X mental retardation, autosomal homolog 2 0 1
MIRT439130 DLX1 distal-less homeobox 1 0 1
MIRT439131 CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0 1
MIRT439132 ASCL2 achaete-scute complex homolog 2 (Drosophila) 0 1
MIRT439134 ANXA7 annexin A7 0 1
MIRT448050 SFRP1 secreted frizzled-related protein 1 1 1
MIRT459964 POC1A POC1 centriolar protein homolog A (Chlamydomonas) 1 1
MIRT466174 TMED5 transmembrane emp24 protein transport domain containing 5 1 1
MIRT470411 PPP1R15B protein phosphatase 1, regulatory subunit 15B 1 1
MIRT475884 H3F3C H3 histone, family 3C 1 5
MIRT475918 H3F3B H3 histone, family 3B (H3.3B) 1 4
MIRT493172 MKNK2 MAP kinase interacting serine/threonine kinase 2 1 1
MIRT497271 GRK6 G protein-coupled receptor kinase 6 1 1
MIRT498894 RBM12B RNA binding motif protein 12B 1 2
MIRT506896 KCTD11 potassium channel tetramerisation domain containing 11 1 5
MIRT506958 HOXB3 homeobox B3 1 2
MIRT507099 GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) 1 1
MIRT508099 ANKRD33B ankyrin repeat domain 33B 1 2
MIRT508627 PLA2G2C phospholipase A2, group IIC 1 1
MIRT510734 SON SON DNA binding protein 1 3
MIRT513974 CNOT6 CCR4-NOT transcription complex, subunit 6 1 1
MIRT514261 S1PR2 sphingosine-1-phosphate receptor 2 1 1
MIRT514576 MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 1 2
MIRT515043 EBNA1BP2 EBNA1 binding protein 2 1 1
MIRT515691 TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1 1
MIRT515751 ONECUT3 one cut homeobox 3 1 1
MIRT517388 METTL7A methyltransferase like 7A 1 1
MIRT519731 ZNF460 zinc finger protein 460 1 1
MIRT520246 USP9X ubiquitin specific peptidase 9, X-linked 1 2
MIRT520269 URGCP upregulator of cell proliferation 1 1
MIRT522214 NR2C2 nuclear receptor subfamily 2, group C, member 2 1 3
MIRT523699 FHL2 four and a half LIM domains 2 1 2
MIRT523979 DVL3 dishevelled, dsh homolog 3 (Drosophila) 1 1
MIRT525568 MTRNR2L7 MT-RNR2-like 7 1 3
MIRT525618 MTRNR2L3 MT-RNR2-like 3 1 2
MIRT530222 UGDH UDP-glucose 6-dehydrogenase 1 1
MIRT530548 SYNPO synaptopodin 1 1
MIRT531040 ZNF502 zinc finger protein 502 1 1
MIRT532578 GSS glutathione synthetase 1 1
MIRT534839 RAB15 RAB15, member RAS oncogene family 1 1
MIRT535792 MTRNR2L11 MT-RNR2-like 11 (pseudogene) 1 3
MIRT535810 MTRNR2L10 MT-RNR2-like 10 1 2
MIRT536817 HMGN2 high mobility group nucleosomal binding domain 2 1 1
MIRT539892 IRGQ immunity-related GTPase family, Q 1 1
MIRT540207 ARHGAP18 Rho GTPase activating protein 18 1 1
MIRT540950 SLC25A43 solute carrier family 25, member 43 1 1
MIRT541935 ORC1 origin recognition complex, subunit 1 1 2
MIRT542194 FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 1 3
MIRT542373 PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1 1
MIRT542507 WDR13 WD repeat domain 13 1 1
MIRT542574 ZNF280B zinc finger protein 280B 1 1
MIRT542713 RPS15A ribosomal protein S15a 1 1
MIRT546706 RORA RAR-related orphan receptor A 1 2
MIRT549622 TMEM101 transmembrane protein 101 1 1
MIRT549928 NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 1 1
MIRT550161 ZNF223 zinc finger protein 223 1 2
MIRT554083 SNX4 sorting nexin 4 1 2
MIRT558567 CRLF3 cytokine receptor-like factor 3 1 2
MIRT560944 TPM4 tropomyosin 4 1 2
MIRT568634 ACVR2A activin A receptor, type IIA 1 1
MIRT574847 CADM1 cell adhesion molecule 1 1 1
MIRT575175 Atg9a autophagy related 9A 1 1
MIRT576663 Fam216a RIKEN cDNA 1500011H22 gene 1 1
MIRT609433 MTX3 metaxin 3 1 1
MIRT617413 API5 apoptosis inhibitor 5 1 1
MIRT617468 CCS copper chaperone for superoxide dismutase 1 1
MIRT618779 HLA-E major histocompatibility complex, class I, E 1 1
MIRT618834 PHF20 PHD finger protein 20 1 1
MIRT619338 RNF2 ring finger protein 2 1 1
MIRT625243 C6orf89 chromosome 6 open reading frame 89 1 1
MIRT626438 CHDH choline dehydrogenase 1 1
MIRT634927 CHMP1B charged multivesicular body protein 1B 1 1
MIRT635874 SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 1 1
MIRT636234 SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 1 1
MIRT636640 CHAF1B chromatin assembly factor 1, subunit B (p60) 1 1
MIRT640544 C3orf36 chromosome 3 open reading frame 36 1 1
MIRT648660 ALKBH4 alkB, alkylation repair homolog 4 (E. coli) 1 1
MIRT650185 LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 1 1
MIRT650789 GSR glutathione reductase 1 1
MIRT652026 TTYH3 tweety homolog 3 (Drosophila) 1 1
MIRT652516 TMEM109 transmembrane protein 109 1 1
MIRT661939 MAVS mitochondrial antiviral signaling protein 1 1
MIRT661950 FAHD1 fumarylacetoacetate hydrolase domain containing 1 1 1
MIRT662019 ZNF445 zinc finger protein 445 1 1
MIRT664014 LOH12CR1 loss of heterozygosity, 12, chromosomal region 1 1 1
MIRT664058 KIAA1551 KIAA1551 1 1
MIRT666871 POU2F2 POU class 2 homeobox 2 1 1
MIRT669167 CCNG1 cyclin G1 1 1
MIRT673242 KLHDC8A kelch domain containing 8A 1 1
MIRT680409 SFT2D2 SFT2 domain containing 2 1 1
MIRT680483 ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide 1 1
MIRT683576 CARD8 caspase recruitment domain family, member 8 1 1
MIRT684397 MCTS1 malignant T cell amplified sequence 1 1 1
MIRT684557 ZNF708 zinc finger protein 708 1 1
MIRT685420 ACAD8 acyl-CoA dehydrogenase family, member 8 1 1
MIRT686049 SLC5A5 solute carrier family 5 (sodium iodide symporter), member 5 1 1
MIRT687954 HHIP hedgehog interacting protein 1 1
MIRT688180 FRRS1 ferric-chelate reductase 1 1 1
MIRT688302 FAM208A family with sequence similarity 208, member A 1 1
MIRT688899 C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 1 1
MIRT689204 ZNF574 zinc finger protein 574 1 1
MIRT689916 ACOT13 acyl-CoA thioesterase 13 1 1
MIRT692930 EXOSC2 exosome component 2 1 1
MIRT693631 CENPL centromere protein L 1 1
MIRT694761 FZD2 frizzled family receptor 2 1 1
MIRT695372 PHAX phosphorylated adaptor for RNA export 1 1
MIRT696629 WDR77 WD repeat domain 77 1 1
MIRT696689 APOC3 apolipoprotein C-III 1 1
MIRT697366 ZNF394 zinc finger protein 394 1 1
MIRT697610 XIAP X-linked inhibitor of apoptosis 1 1
MIRT697736 USP6NL USP6 N-terminal like 1 1
MIRT697787 UBXN7 UBX domain protein 7 1 1
MIRT698360 TMEM127 transmembrane protein 127 1 1
MIRT704518 CNKSR3 CNKSR family member 3 1 1
MIRT704599 CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) 1 1
MIRT705848 AHCY adenosylhomocysteinase 1 1
MIRT707092 TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) 1 1
MIRT707153 C17orf105 chromosome 17 open reading frame 105 1 1
MIRT707242 H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1 1
MIRT707354 XPNPEP3 X-prolyl aminopeptidase (aminopeptidase P) 3, putative 1 1
MIRT707458 PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 1 1
MIRT707502 AXL AXL receptor tyrosine kinase 1 1
MIRT707646 CRIPT cysteine-rich PDZ-binding protein 1 1
MIRT707702 FAM118A family with sequence similarity 118, member A 1 1
MIRT707713 CDC6 cell division cycle 6 homolog (S. cerevisiae) 1 1
MIRT707824 TMEM170A transmembrane protein 170A 1 1
MIRT707965 PDK3 pyruvate dehydrogenase kinase, isozyme 3 1 1
MIRT708005 NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 1 1
MIRT708034 MRPS14 mitochondrial ribosomal protein S14 1 1
MIRT708072 LIX1L Lix1 homolog (mouse)-like 1 1
MIRT708130 GK5 glycerol kinase 5 (putative) 1 1
MIRT708199 ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 1 1
MIRT708208 AHSA2 AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast) 1 1
MIRT708939 CRY2 cryptochrome 2 (photolyase-like) 1 1
MIRT709198 SAPCD2 suppressor APC domain containing 2 1 1
MIRT714402 FBXO31 F-box protein 31 1 1
MIRT714628 KIAA1143 KIAA1143 1 1
MIRT720740 ELOVL7 ELOVL fatty acid elongase 7 1 1
MIRT720893 CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 1 1
MIRT723334 DGAT1 diacylglycerol O-acyltransferase 1 1 1
MIRT724451 OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 1 1
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